ProTools|HD Native is designed to enable you to compose, record, edit, and mix music and/or sound for picture.
A complete Pro Tools|HD Native system is comprised of the following:
Choice of HD Native Thunderbolt interface or PCIe card
Unlike USB- or FireWire-based DAWs, which are said to be inherently prone to latency, Pro Tools|HD Native employs either a high-speed Thunderbolt interface or PCIe core card to connect Pro Tools HD Series interfaces with your laptop or desktop computer.
Check out Avid for more details.